Roles of Keap1–Nrf2 System in Upper Aerodigestive Tract Carcinogenesis
نویسندگان
چکیده
منابع مشابه
Retinoid chemoprevention studies in upper aerodigestive tract and lung carcinogenesis.
Chemoprevention is a clinical strategy to block or reverse carcinogenesis before the development of invasive cancer. Studies of chemoprevention in the lungs and upper aerodigestive tract have relied on the field carcinogenesis hypothesis, which predicts that diffuse epithelial injury will result from exposure of that epithelium to carcinogens. This hypothesis is supported by the frequent occurr...
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Introduction: We present a retrospective study series and discussion of the current literature to discuss the management of fishbones in the upper aerodigestive tract. Materials and Methods: From January 2013 to July 2016, all patients referred to our referral center because of a fishbone in the upper aerodigestive tract were analysed. Results: Of the 24 patients, 95% of them reported disc...
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Reflux disease can cause multiple disorders not only of the esophagus but also of the upper aerodigestive tract. In the last decade, an association between reflux disease and multiple head and neck diseases was described, including those of the larynx and pharynx as well as those of the nose, the sinuses and the middle ear. The present article summarizes these different diseases and possible pa...
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BACKGROUND High risk head and neck mucosal premalignancy has a malignant conversion rate of up to 40%, despite adequate surgical therapy. Epidermal Growth Factor Receptor (EGFR) blocking agents, including cetuximab, have shown activity in head and neck squamous cell carcinoma (HNSCC) and have potential for therapy in high risk premalignancy. METHODS We conducted a randomized, prospective, pha...
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ژورنال
عنوان ژورنال: Cancer Prevention Research
سال: 2012
ISSN: 1940-6207,1940-6215
DOI: 10.1158/1940-6207.capr-12-0401-t